The residues with NA values for either state are not shown.
The residues with NA values for either state are not shown.
Method of calculation:
For every time point of uptake curve for two states it is recognized which state has higher value and which has lower. From the higher value the uncertainty value is substracted to have the lowest possible value. To the lower value the uncertainty value is added to get the highest possible value. Now, the difference between this two values is calculated - if the difference is negative is changed to zero as the possible value ranges overlap. Values from all of the time points are summed to get one value of difference between uptake curves for each peptide.
Classification results for the first state:
Classification results for the second state:
Classification components for the first state:
Classification components for the second state:
To make the image of the structure, set the protein in desired position, stop the spinning and make a screen shot.
Welcome to the compaHRaDeX app!
compaHRaDeX is a part of tool family for exploring the data from HDX-MS experiments. Those tools are developed in Mass Spectrometry Lab in Institute of Biophysics and Biochemistry, Polish Academy of Sciences.
compahradex is the tool to compare classification results for two biological states. Classification results for each state separately are obtained using HRaDeX. For overall analysis on peptide level, use HaDeX 2.0.
Contact us at: hadex@ibb.waw.pl.
This work is part of 2019/35/O/NZ2/03745 grant from National Science Centre in Poland. The hadexversum project originated within the TEAM TECH programme of the Foundation for Polish Science co-financed by the European Union under the European Regional Development Fund (TEAM TECH CORE FACILITY/2016-2/2).
